Nikki Glaser doesn’t want people who don’t use Ozempic to judge those who do.
The comedian and recent Golden Globes host appeared on The Tonight Show Starring Jimmy Fallon on Monday (March 24), sharing her take on the medication around the four-minute mark below. While Ozempic has become popular for weight loss, it was originally created to treat Type 2 diabetes. Celebrities like Amy Schumer, Kelly Osbourne, and Tracy Morgan have openly discussed using Ozempic. The injectable drug contains semaglutide, which boosts insulin and controls appetite.
Glaser, who’s planning to get a facelift, started by discussing “investing” in appearance, noting that “people treat you better when you’re hotter.” When Fallon asked the 40-year-old about her thoughts on Ozempic.
“Oh, I love it, I love it. I’m like, do it, do it. I have no judgment. If you want to do Ozempic, hell yeah, girl,” Glaser told Fallon. “I want people to feel more comfortable talking about doing it, because I feel like there’s, like, this shame—and the shame is only from thin people who want you to stay fat. Like that’s really where it’s coming from.”
“They are so mad that you’re getting thin now, because that’s all they have, right? They are so mad, but they can’t say it. They just go, ‘No! You’re stealing medicine from diabetics who need it.’ Like, that’s their excuse,” she continued. “It’s suddenly all these thin, white women are like ‘diabetics need their meds.’ No, I think you’re upset that Kathy Bates has a thigh gap. That’s more what it could be about, I think.”
But among Ozempic’s famous critics is actress Jameela Jamil, who battled an eating disorder in her teens and twenties.
“May I have the strength through this era of Ozempic heroin chic, in my industry to keep up this good work I did on my brain throughout 2025,” she wrote in an Instagram post in December. “I would rather leave this industry than get dragged back.”